Sudafed Buying Guide & Brand Review (Sep. 2026 Updated)

Sudafed Nasal Spray

Features

Nose spray

Unblocks your nose fast

Show More

Sudafed PE Sinus Pressure + Pain Relief Tablets, Maximum Strength, Non-Drowsy, Acetaminophen, Pain Reliever, Fever Reducer, Phenylephrine HCl, Decongestant, Sinus Congestion Relief; 24 ct; Pack of 1

Features

DECONGESTANT & PAIN RELIEF: Sudafed PE Sinus Pressure and Pain is a maximum strength non-drowsy decongestant tablet for fast and powerful relief of sinus congestion, sinus pressure, and nasal congestion.

NON-DROWSY ALLERGY MEDICINE: Sudafed sinus and pain medication helps to temporarily relieve nasal congestion associated with hay fever, upper respiratory allergies and the common cold; a nasal decongestant that provides non-drowsy symptom relief.

Show More

Sudafed PE Sinus Congestion Relief Tablets, Maximum Strength, Non-Drowsy, 10 mg Phenylephrine HCI Nasal Decongestant for Sinus Pressure and Congestion Due to Cold or Allergies, 36 ct

Features

Sinus pressure & congestion relief: 36-count package of Sudafed PE sinus congestion maximum strength; a non-drowsy decongestant tablet for fast and relief of sinus pressure and sinus and nasal congestion

Non-drowsy cold & sinus medicine: Sudafed sinus congestion and cold relief medication helps to temporarily relieve nasal congestion associated with hay fever, upper respiratory allergies and the common cold

Show More

Sudafed Pe Sinus Congestion Relief Tablets, Maximum Strength, Non-Drowsy 10 Mg Phenylephrine Hci Decongestant for Sinus Pressure & Nasal Congestion Relief from Colds Or Allergies, 18 Ct

Features

SINUS PRESSURE & CONGESTION RELIEF: 18-count package of Sudafed PE Sinus Congestion, a maximum strength non-drowsy decongestant tablet for fast and powerful relief of sinus pressure and sinus and nasal congestion

NON-DROWSY COLD & SINUS MEDICINE: Sudafed sinus congestion and cold relief medication helps to temporarily relieve nasal congestion associated with hay fever, upper respiratory allergies and the common cold for non-drowsy symptom relief

Show More

Sudafed PE Day and Night Sinus Pressure & Congestion Tablets, 20 Count

Features

20-count of Sudafed PE Sinus Congestion Day + Night Maximum Strength Decongestant Medicine Tablets to temporarily relieve sinus pressure and sinus congestion for both day and night

Each multi-pack contains 20 tablets of nasal decongestant, with 12 Daytime and 8 Nighttime tablets for powerful symptom relief throughout the day and while you sleep

Show More

Sudafed PE Head Congestion Plus Mucus Relief Tablets for Sinus Pressure, Congestion and Headache, Non-Drowsy Decongestant with Acetaminophen, Guaifenesin, Phenylephrine HCI, 24 ct

Features

24-count box of Sudafed PE: Head Congestion + Mucus Tablets to provide non-drowsy relief from sinus pain and pressure, nasal & chest congestion, and excess mucus

Sinus medicine contains: 5 mg of phenylephrine HCl, a decongestant, for congestion relief and 325 mg of acetaminophen for pain and fever reduction; also 200 mg of guaifenesin, an expectorant for mucus reduction

Show More

Sudafed PE Head Congestion + Pain Relief Caplets Ibuprofen Phenylephrine HCl, 20 Count

Features

20-count of Sudafed PE Non-Drowsy Head Congestion + Pain Relief Caplets for effective nasal congestion relief and nasal swelling relief, now coupled with the powerful pain relief of ibuprofen

From the #1 pharmacist recommended brand among oral OTC decongestants, it provides non-drowsy relief from head congestion and pain symptoms caused by head colds

Show More

Sudafed Children's PE Nasal Decongestant Liquid, Sugar-Free Cold Medicine with Phenylephrine HCl, Alcohol-Free, Berry-Flavored, 4 fl oz

Features

4-fluid ounces: of Children's Sudafed PE Nasal Decongestant provides temporary relief for children's nasal congestion and sinus pressure due to the common cold and hay fever

Non-drowsy nasal decongestant: formula is alcohol-free and sugar-free and includes the active ingredient of phenylephrine HCl

Show More

Sudafed Children's PE Nasal Decongestant, Liquid Cold Relief Medicine with Phenylephrine HCl, Alcohol Free and Sugar-Free, Berry-Flavored, 4 fl. oz (Pack of 2)

Features

The information below is per-pack only

4-fluid ounces of Children's Sudafed PE Nasal Decongestant provides temporary relief for children's nasal congestion and sinus pressure due to the common cold and hay fever

Show More

Sudafed PE Head Congestion + Mucus Relief Tablets for Sinus Pressure, Congestion, & Headache, Non-Drowsy Decongestant with Acetaminophen, Guaifenesin & Phenylephrine HCI, 24 ct

Features

24-count box of Sudafed PE Head Congestion + Mucus Tablets to provide non-drowsy relief from sinus pain and pressure, nasal & chest congestion, and excess mucus

Sinus relief medicine contains 5 mg of phenylephrine HCl, a decongestant, for congestion relief and 325 mg of acetaminophen for pain and fever reduction. Also has 200 mg of guaifenesin, an expectorant, for mucus reduction

Show More

Sudafed Non-Medicated Saline Nasal Mist with Aloe, Sinus Saline Nose Spray for All Ages Quickly Flushes & Moisturizes Nasal Passages, Use Nasal Mist as Often As Needed, Drug-Free, 3 fl. oz

Features

3-fluid ounce spray bottle of Sudafed Non-Medicated Saline Nasal Mist with Aloe for all ages works quickly to flush out and hydrate noses for dry nasal passage relief

Suitable for the whole family, this nasal spray is formulated with three simple ingredients for every day use: aloe, salt, and water. The gentle and hydrating formula allows this nasal moisturizer to be used as often as needed

Show More

SUDAFED PE Pressure + Pain Maximum Strength Caplets for Adults 24 ea (Pack of 4)

Features

Maximum Strength Formula: Contains active ingredients formulated to ease head pressure during routine activities. Caplet format is simple to consume and store.

Designed for Adults: Tailored for adult use with clearly labeled dosing instructions. Compact packaging makes it suitable for home or travel.

Show More

Children's Sudafed Pe Non-drowsy Raspberry Flavor Liquid, 4-Ounce (Pack of 2)

Features

Stuffy Nose

Sinus Pressure

Show More

Sudafed PE Congestion and Sinus Pressure Relief Tablets, Non-Drowsy Maximum Strength Nasal Decongestant with Phenylephrine HCI, 18 ct (Pack of 2)

Children's Sudafed PE Nasal Decongestant with Phenylephrine HCl, Berry-Flavored Liquid, 4 fl. oz

Features

4-fluid ounces of Children's Sudafed PE Nasal Decongestant provides temporary relief for children's nasal congestion and sinus pressure due to the common cold and hay fever

Non-drowsy nasal decongestant formula that is alcohol-free and sugar-free and includes the active ingredient of phenylephrine HCl as a nasal decongestant

Show More