Top 27 Frontline Dog Flea Drops on Amazon (Verified You can Buy)
Top 1
Frontline Plus for Dogs Medium Dog (23-44 pounds) Flea and Tick Treatment, 6 Doses
Frontline
74274
5.75 x 1.0 x 4.5 inches
0.1 pounds
Ratings for Frontline (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ❌ | ❌ | ❌ |
Features
The #1 name in flea and tick protection
Trusted by pet owners for over 20 years**
Top 2
FRONTLINE® Plus for Dogs Flea and Tick Treatment (Extra Large Dog, 89-132 lbs.) 6 Doses (Red Box)
Frontline
72220
2.0 x 5.4 x 0.15 inches
0.02 pounds
- Designer: Pro Med LLC
Ratings for Frontline (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
Features
Keep your dog protected from fleas & ticks all month long with FRONTLINE Plus for Dogs a fast-acting, waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease.
Break the flea life cycle with FRONTLINE Plus. Specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control.
Top 3
Best for 80 to 89 Pounds
FRONTLINE Shield Flea & Tick Treatment for Large Dogs 41-80 lbs. Count of 3
Frontline
850
0.74 x 5.795 x 4.394 inches
0.0906 pounds
Ratings for Frontline (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ❌ | ❌ | ❌ |
Features
FRONTLINE Shield provides proven flea and tick protection with repellency action against ticks and mosquitoes
Kills and repels all stages of ticks, including those that may transmit Lyme disease
Top 4
FRONTLINE Plus Flea & Tick Spot Treatment for Large Breed Dogs 45-88 lbs. (Purple) Count of 8
Frontline
72219
1.0 x 5.75 x 4.5 inches
0.15 Pounds
Ratings for Frontline (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ❌ | ❌ | ❌ |
Features
The #1 name in flea and tick protection
Trusted by pet owners for over 20 years**
Top 5
FRONTLINE Plus for Dogs Flea and Tick Treatment (Small Dog, 5-22 lbs.) 8 Doses (Orange Box)
Frontline
74273
0.63 x 5.75 x 4.5 inches
0.03 pounds
Ratings for Frontline (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ❌ | ❌ | ❌ |
Features
Keep your dog protected from fleas & ticks all month long with FRONTLINE Plus for Dogs a fast-acting, waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease
Break the flea life cycle with FRONTLINE Plus, specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control
Top 6
FRONTLINE Plus Flea and Tick Treatment for Small Dogs Upto 5 to 22 lbs., 6 Treatments
Frontline
74273
5.75 x 1.0 x 4.5 inches
0.1 pounds
- Designer: Pro Med LLC
Ratings for Frontline (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
Features
Keep your dog protected from fleas & ticks all month long with FRONTLINE Plus for Dogs a fast-acting, waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease.
Break the flea life cycle with FRONTLINE Plus. Specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control.
Top 7
FRONTLINE Shield Flea & Tick Treatment for Medium Dogs 21-40 lbs. Count of 3
Frontline
849
0.74 x 5.795 x 4.394 inches
0.09 Pounds
Ratings for Frontline (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ❌ | ❌ | ❌ |
Features
FRONTLINE Shield provides proven flea and tick protection with repellency action against ticks and mosquitoes
Kills and repels all stages of ticks, including those that may transmit Lyme disease
FRONTLINE® Plus for Dogs Flea and Tick Treatment (Small Dog, 5-22 lbs.) 3 Doses (Orange Box)
Frontline
74273
5.75 x 0.75 x 4.5 inches
0.05 Pounds
Ratings for Frontline (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
Features
Keep your dog protected from fleas & ticks all month long with FRONTLINE Plus for Dogs a fast-acting, waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease.
Break the flea life cycle with FRONTLINE Plus. Specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control.
FRONTLINE Plus Flea and Tick Treatment for Large Dogs Up to 45 to 88 lbs., 3 Treatments
Frontline
72219
5.75 x 0.75 x 4.5 inches
0.04 pounds
Ratings for Frontline (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
Features
Keep your dog protected from fleas & ticks all month long with FRONTLINE Plus for Dogs a fast-acting, waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease.
Break the flea life cycle with FRONTLINE Plus. Specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control.
Top 10
FRONTLINE Shield Flea & Tick Treatment for X-Large Dogs 81-120 lbs., Count of 3
Frontline
851
0.74 x 5.795 x 4.394 inches
Ratings for Frontline (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
Features
FRONTLINE Shield, from the #1 name in flea and tick protection*, provides proven flea and tick protection with repellency action against ticks and mosquitoes.* Data on file at Boehringer Ingelheim.
Kills and repels all stages of ticks, including those that may transmit Lyme disease.
Top 11
Best for 80 to 89 Pounds
Frontline Plus for Dogs Large Dog (45 to 88 pounds) Flea and Tick Treatment, 6 Doses
Frontline
72219
5.75 x 1.0 x 4.5 Inches
0.01 pounds
- Designer: Pro Med LLC
Ratings for Frontline (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ❌ | ❌ | ❌ |
Features
The #1 name in flea and tick protection
Trusted by pet owners for over 20 years**
Top 12
FRONTLINE Plus Flea and Tick Treatment for Medium Dogs Up to 23 to 44 lbs, 3 Treatments
Frontline
74269
5.75 x 0.75 x 4.5 inches
0.2 Pounds
Ratings for Frontline (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
Features
Keep your dog protected from fleas & ticks all month long with FRONTLINE Plus for Dogs a fast-acting, waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease.
Break the flea life cycle with FRONTLINE Plus. Specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control.
Top 13
FRONTLINE Plus Flea and Tick Treatment for X-Large Dogs Up to 89 to 132 lbs., 3 Treatments
Frontline
72220
5.75 x 0.75 x 4.5 inches
0.1 Pounds
Ratings for Frontline (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
Features
Keep your dog protected from fleas & ticks all month long with FRONTLINE Plus for Dogs a fast-acting, waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease.
Break the flea life cycle with FRONTLINE Plus. Specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control.
Top 14
Frontline Gold Flea & Tick Treatment for Medium Dogs Up to 23 to 44 lbs., Pack of 3
Frontline
00872
0.02 pounds
Ratings for Frontline (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
Features
From the #1 Name in Flea and Tick Protection* *Data on file at Boehringer Ingelheim.
Easy to use flea and tick protection for dogs
Top 15
Frontline Gold for Dogs 89132 lbs Red (6 Month)
Frontline
Frontline Gold for Dogs 89 - 132 lbs Red
0.1 pounds
Ratings for Frontline (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
| Pets Go Here - Pet Store | 4,545 | ✅ | ✅ | ✅ |
Features
New easy to use applicator
Frontline gold has a new and improved triple action formula
Top 16
FRONTLINE® Shield for Dogs 3-in-1 Flea and Tick Treatment (Small Dog, 11- 20 lbs.) 3 Doses (Orange Box)
Frontline
848
0.74 x 5.795 x 4.394 inches
0.05 Pounds
Ratings for Frontline (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
Features
FRONTLINE Shield, from the #1 name in flea and tick protection*, provides proven flea and tick protection with repellency action against ticks and mosquitoes.* Data on file at Boehringer Ingelheim.
Kills and repels all stages of ticks, including those that may transmit Lyme disease.
Top 17
Best for 50 to 59 Pounds
Frontline Gold Flea & Tick Treatment for X-Large Dogs Up to 89 to 132 lbs., Pack of 3
Frontline
00874
0.0266 pounds
Ratings for Frontline (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
Features
From the #1 Name in Flea and Tick Protection* *Data on file at Boehringer Ingelheim.
Easy to use flea and tick protection for dogs
Top 18
Best for 50 to 59 Pounds
Frontline Gold Flea & Tick Treatment for Small Dogs Up to 5 to 22 lbs., Pack of 3
Frontline
00871
0.011 Pounds
Ratings for Frontline (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
Features
From the #1 Name in Flea and Tick Protection* *Data on file at Boehringer Ingelheim.
Easy to use flea and tick protection for dogs
Top 19
Frontline Shield Flea & Tick Treatment for X-Small Dogs 5-10 lbs., Count of 3
Frontline
847
0.74 x 5.795 x 4.394 inches
0.0198 Pounds
Ratings for Frontline (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
Features
FRONTLINE Shield, from the #1 name in flea and tick protection*, provides proven flea and tick protection with repellency action against ticks and mosquitoes.* Data on file at Boehringer Ingelheim.
Kills and repels all stages of ticks, including those that may transmit Lyme disease.
Top 20
FRONTLINE Shield Flea & Tick Treatment for Large Dogs 41-80 lbs., Count of 6
Frontline
855
1.48 x 5.795 x 4.394 inches
Ratings for Frontline (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
Features
FRONTLINE Shield, from the #1 name in flea and tick protection*, provides proven flea and tick protection with repellency action against ticks and mosquitoes.* Data on file at Boehringer Ingelheim.
Kills and repels all stages of ticks, including those that may transmit Lyme disease.
Top 21
Frontline Shield Flea & Tick Treatment for Medium Dogs 21-40 lbs., Count of 6
Frontline
854
1.48 x 5.795 x 4.394 inches
0.1102 pounds
Ratings for Frontline (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
Features
FRONTLINE Shield, from the #1 name in flea and tick protection*, provides proven flea and tick protection with repellency action against ticks and mosquitoes.* Data on file at Boehringer Ingelheim.
Kills and repels all stages of ticks, including those that may transmit Lyme disease.
Top 22
Frontline Plus Medium Dog
Frontline
6.0 x 4.0 x 1.0 inches
0.1 Pounds
Ratings for Frontline (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Pets Go Here - Pet Store | 4,545 | ✅ | ✅ | ✅ |
| Pets with Panache | - | ✅ | ✅ | ✅ |
| WOOFthful Dog | - | ✅ | ✅ | ✅ |
Features
EPA approved
23-44 LB Medium Dogs
Top 23
FRONTLINE Shield Flea & Tick Treatment for Small Dogs 11-20 lbs. Count of 6
Frontline
853
1.48 x 5.795 x 4.394 inches
0.1102 pounds
Ratings for Frontline (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ❌ | ❌ | ❌ |
Features
FRONTLINE Shield provides proven flea and tick protection with repellency action against ticks and mosquitoes
Kills and repels all stages of ticks, including those that may transmit Lyme disease
Top 24
FRONTLINE® Gold for Dogs Flea & Tick Treatment (Medium Dog, 23-44 lbs.) 6 Doses (Blue Box)
Frontline
00877
0.0022 pounds
Ratings for Frontline (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
| tranaction | - | ✅ | ✅ | ✅ |
Features
From the #1 Name in Flea and Tick Protection* *Data on file at Boehringer Ingelheim.
Easy to use flea and tick protection for dogs
Top 25
FRONTLINE Gold Flea & Tick Treatment for X-Large Dogs Up to 89 to 132 lbs., Pack of 6
Frontline
00879
0.0266 pounds
Ratings for Frontline (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
Features
From the #1 Name in Flea and Tick Protection* *Data on file at Boehringer Ingelheim.
Easy to use flea and tick protection for dogs
Top 26
FRONTLINE Plus Flea and Tick Treatment for Medium Dogs Up to 23 to 44 lbs., 8 Treatments
Frontline
72218
0.63 x 5.75 x 4.5 inches
0.02 pounds
Ratings for Frontline (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
| Petco Supplies | 230 | ✅ | ✅ | ✅ |
Features
Keep your dog protected from fleas & ticks all month long with FRONTLINE Plus for Dogs a fast-acting, waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease.
Break the flea life cycle with FRONTLINE Plus. Specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control.
Top 27
FRONTLINE Shield Flea & Tick Treatment for Dogs 5-10 lbs. (Pink) Count of 6
Frontline
852
1.48 x 5.795 x 4.394 inches
0.09 pounds
Ratings for Frontline (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ❌ | ❌ | ❌ |
Features
Starts killing fleas in 5 minutes* and starts killing ticks in 1 hour**
Kills and repels of ticks, including ticks that may transmit Lyme disease
Top 10 Frontline Dog Flea Drops - Verified to Buy (September 2026)
- 1. Frontline Plus for Dogs Medium Dog (23-44 pounds) Flea and...
- 2. FRONTLINE® Plus for Dogs Flea and Tick Treatment (Extra Large...
- 3. FRONTLINE Shield Flea & Tick Treatment for Large Dogs 41-80...
- 4. FRONTLINE Plus Flea & Tick Spot Treatment for Large Breed...
- 5. FRONTLINE Plus for Dogs Flea and Tick Treatment (Small Dog,...
- 6. FRONTLINE Plus Flea and Tick Treatment for Small Dogs Upto...
- 7. FRONTLINE Shield Flea & Tick Treatment for Medium Dogs 21-40...
- 8. FRONTLINE® Plus for Dogs Flea and Tick Treatment (Small Dog,...
- 9. FRONTLINE Plus Flea and Tick Treatment for Large Dogs Up...
- 10. FRONTLINE Shield Flea & Tick Treatment for X-Large Dogs 81-120...
Related Frontline Dog Flea Drops Guides
For more personalized Frontline Dog Flea Drops guides, Check those pages,
Featured Brands
Top 5 Frontline Dog Flea Drops Sellers: CPR Seller Rank List
CPR sellers rank is based on CherryPicks-AI bestselling ranking system that helps us analyze each seller's sales trends. The List of top seller ranks is our in-house data, essential for our product ranking to help you make the right shopping choice.
- 1. Petco Supplies : 156,560 Yearly Feedback , Avg. Ratings 4.5
- 2. Pets Go Here - Pet Store : 14,331 Yearly Feedback , Avg. Ratings 4.8
- 3. Pets with Panache : 2,942 Yearly Feedback , Avg. Ratings 4.8
- 4. tranaction : 921 Yearly Feedback , Avg. Ratings 4.7
- 5. Amazon.com : 386 Yearly Feedback , Avg. Ratings 4.7
| Rank | Name | Yearly Feedbacks | Avg. Ratings |
|---|---|---|---|
| 🥇 | Petco Supplies | 156,560 | 4.5 |
| 🥈 | Pets Go Here - Pet Store | 14,331 | 4.8 |
| 🥉 | Pets with Panache | 2,942 | 4.8 |
| 4 | tranaction | 921 | 4.7 |
| 5 | Amazon.com | 386 | 4.7 |
[Get] Frontline Dog Flea Drops Deals (✅Exclusively for Prime)
What does "Amazon Fulfilled" Mean?
Amazon Fulfilled refers to products handled by Amazon's logistics, which indicates that the product is stored, packed, and shipped by Amazon from one of its fulfillment centers.
When you order a product that is "Amazon Fulfilled," Amazon takes care of the storage, packing, shipping, and customer service for that product. This often ensures quicker delivery and better customer service compared to products that are not fulfilled by Amazon. It also means that the product is eligible for Amazon's return policy.
What does "Prime" Mean?
"Prime" refers to Amazon Prime Member (Join Amazon Prime Now), which indicates eligibility for Prime benefits. When you see "Prime" next to a product on Amazon, This generally means that if you are an Amazon Prime member, you can get free two-day shipping on that product, and sometimes even same-day or one-day shipping depending on your location.
Prime members also have access to other benefits, including 2-Day Shipping, Exclusive Member Deals, Prime Video, Buy With Prime, Amazon Music, Prime Gaming, and more.
Shop Prime Frontline Dog Flea Drops Deals
What does "Free Shipping" Mean?
"Free Shipping" means that you will not be charged additional fees for the shipping of that product. However, unlike "Prime," which usually guarantees fast two-day shipping, "Free Shipping" doesn't necessarily mean fast shipping.
Sometimes there might be a minimum purchase requirement to qualify for free shipping if you are not a Prime member. For Prime members, the "Free Shipping" usually refers to the free two-day shipping that is one of the benefits of the Prime membership.
Why Should You Trust Us?
Now hundreds and thousands of Dogs supplies are available on Amazon, Picking the right one is not easy, and that may take a lot of your time, Right? and What is the best Frontline Dog Flea Drops to buy for new September 2026?
CherryPicks’s Methodology for Evaluating Frontline Dog Flea Drops
We developed the CherryRatings-AI system to identify and score reviews and the CherryPicks-AI ranking system that uses TensorFlow framework to generate the best list, It will help us evaluate Dogs items that sell on Amazon. The score of items is based on over ten parameters such as analyzing customer review content, product reviewing rating statistics, brand reputation evaluation, comparing product price with features, etc, You can visit How We Rank to learn more in detail.
We collected and analyzed 27 of Frontline Dog Flea Drops reviews based on our selection criteria. It helped us shortlist the top qualified and rated Frontline Dog Flea Drops for Dogs, We found that most customers choose Frontline Dog Flea Drops with an average price of $64.29, and the top brands are Frontline.
Then our expert-level editors reviewed all those quality items and selected the top 27 Frontline Dog Flea Drops for you, We have researched hundreds of sellers and picked the top sellers for Dogs, including Petco Supplies, Pets Go Here - Pet Store, Pets with Panache, tranaction And Amazon.com. The Frontline Plus for Dogs Medium Dog (23-44 pound... are available for purchase right now, and The seller of #1 rank product has received honest feedback from 24,043 consumers with an average rating of 4.4.
We've helped a lot of satisfied users get the right Pet Supplies product based on their needs, and save lots of time for them to pick Frontline Dog Flea Drops to buy.
Toby Broun is a seasoned writer whose expertise lies in anything related to pets which his most love topics centered around pet supplies. He would be providing us unbiased and amazing reviews on pet supplies and products. When he is not writing, he is indoor coding — yes, he codes for fun.