Top 30 Non-aspirin Pain Relievers on Amazon (Verified You can Buy)
Top 1
Best OTC Medications & Treatments
Best Acetaminophen
Best for Amazon Basic Care
Best for Caplet
Best for Back Pain
Best for Headache
Best for Muscle Pain
Best for Aspirin
Best for Ibuprofen
Amazon Basic Care Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, Pain Reliever/Fever Reducer, 100 Count
Amazon Basic Care
4.25 x 2.1 x 2.1 Inches
0.1806 pounds
Ratings for Amazon Basic Care (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ❌ | ❌ | ❌ |
Features
ACTIVE INGREDIENT: This pain relief medication contains acetaminophen 500 mg, a pain reliever/fever reducer which compares to the active ingredient of Extra Strength Tylenol Caplets
PAIN RELIEF PILLS: Temporarily relieves minor aches and pains due to the common cold, headache, backache, toothache, muscular aches, and premenstrual and menstrual cramps; also provides minor arthritis pain relief
Top 2
Best OTC Medications & Treatments
Best Pain Relief Medications & Treatments
Best Acetaminophen
Best for Tylenol
Best for Caplet
Best for Fever
Best for Headache
Best for Muscle Pain
Best for Aspirin
Best for Ibuprofen
Tylenol Extra Strength Acetaminophen Rapid Release Gels, Pain Reliever & Fever Reducer, 100 ct
Tylenol
JO48810
1.98 x 3.87 x 2.02 Inches
0.2 Pounds
Ratings for Tylenol (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
Features
100-count Tylenol Extra Strength Rapid Release Gels with acetaminophen work fast to temporarily relieve minor aches and pains and help reduce fever
Each gelcap features unique, laser-drilled holes to quickly release pain medicine and contains 500 mg of acetaminophen for fast, effective extra strength pain relief
Top 3
Best Acetaminophen
Best for Amazon Basic Care
Best for Caplet
Best for Liquid
Best for Syrup
Best for Back Pain
Best for Fever
Best for Headache
Best for Muscle Pain
Best for Inflammation
Best for Aspirin
Amazon Basic Care Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, 200 Count
Amazon Basic Care
1
2.2 x 2.2 x 4.5 Inches
0.24 Pounds
Ratings for Amazon Basic Care (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
Features
ACTIVE INGREDIENT: Amazon Basic Care Extra Strength Pain Relief's active ingredient is Acetaminophen, 500 mg, which compares to the active ingredient of Extra Strength Tylenol Caplets
Amazon Basic Care Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, temporarily relieves minor aches and pains due to: the common cold, headache, backache, minor pain of arthritis, toothache, muscular aches, and premenstrual and menstrual cramps also temporarily reduces fever
Percogesic Extra Strength Pain Reliever, Aspirin Free, Dual Action Relief, Fever Reducer, Antihistamine, 60 Safety Coated Tablets
Percogesic
B001G7QWTY
3.5 x 1.75 x 1.75 Inches
0.1313 Pounds
Ratings for Percogesic (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
Features
Enhanced relief from aches and pain associated with colds, flu, fever, arthritis and more. It also relieves runny noses and sneezing
Pharmacist recommended ingredients, Acetaminophen and Diphenhydramine HCl, provide aspirin free relief that you can trust without worrying about a prescription
Top 5
Best OTC Medications & Treatments
Best Pain Relief Medications & Treatments
Best for Tylenol
Best for Caplet
Best for Back Pain
Best for Muscle Pain
Best for Inflammation
Tylenol 8HR Arthritis Pain Relief Caplets, 650 mg Acetaminophen Pain Relief Pills for Minor Arthritis Pain & Joint Pain, Fever Reducer, Oral Pain Reliever for Joint Pain; 100 ct.; Pack of 1
Tylenol
ASINPRILAK2754
2.22 x 2.22 x 3.84 Inches
0.24 Pounds
Ratings for Tylenol (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
| ISKOLIVE 12 INC | 2,108 | ✅ | ✅ | ✅ |
| EDEN TRADING | - | ✅ | ✅ | ✅ |
Features
ARTHRITIS PAIN RELIEF: Tylenol 8HR Arthritis Pain Extended-Release Caplets with 650 mg acetaminophen caplets provides fast-acting, temporary relief of minor arthritis and joint pain targeted in the hands, wrists, knees, ankles, elbows, and feet.
ACETAMINOPHEN FORMULA: Each Tylenol 8HR Arthritis Pain relief pill contains 650 mg of acetaminophen in each caplet; For effective pain relief of minor arthritis and joint pains; Effective fever reducer.
Top 6
Best for Box
Best for Caplet
Best for Syrup
Best for Back Pain
Best for Muscle Pain
Best for Ibuprofen
Advil Dual Action Coated Caplets with Acetaminophen, 250 Mg Ibuprofen and 500 Mg Acetaminophen Per Dose (2 Dose Equivalent) for 8 Hour Pain Relief - 2 Count x 50
Advil
F00573014795
3.5 x 5.625 x 6.0 inches
0.0006 Pounds
Ratings for Advil (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
Features
50 packets of 2 Advil Dual Action Coated Caplets with Acetaminophen, 250 Mg Ibuprofen and 500 Mg Acetaminophen Per Dose (2 Dose Equivalent) for 8 Hour Pain Relief
Advil Dual Action coated tablets relieve pain with ibuprofen to target pain at the source and acetaminophen to block pain signals, and new packaging will feature 20 percent less plastic to keep nearly 500,000 pounds of plastic out of landfills
HealthA2Z® Pain Relief Extended Release | Acetaminophen 650mg | 8 Hours | Arthiritis Pain | Pain Reliever - Fever Reducer | Contains no Aspirin (100 Count)
HealthA2Z
Ratings for HealthA2Z (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| HealthA2Z | 823 | ❌ | ❌ | ❌ |
Features
🔴 Powerful Pain Relief: Each caplet contains 650 mg of Acetaminophen, providing effective relief from minor aches and pains due to headache, backache, arthritis, muscle pain and toothache
🔴 Extended-Release Formula: Designed for long-lasting pain relief—each dose provides up to 8 hours of comfort so you can stay active and productive throughout the day.
Top 8
Best OTC Medications & Treatments
Best Acetaminophen
Best for Amazon Basic Care
Best for Caplet
Best for Headache
Best for Muscle Pain
Best for Cramps
Best for Aspirin
Amazon Basic Care Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, 1000 Count
Amazon Basic Care
3.75 x 3.75 x 8.0 Inches
0.0838 pounds
Ratings for Amazon Basic Care (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
Features
ACTIVE INGREDIENT: Amazon Basic Care Extra Strength Pain Relief's active ingredient is Acetaminophen, 500 mg, which compares to the active ingredient of Extra Strength Tylenol Caplets
Amazon Basic Care Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, temporarily relieves minor aches and pains due to: the common cold, headache, backache, minor pain of arthritis, toothache, muscular aches, and premenstrual and menstrual cramps also temporarily reduces fever
Top 9
Best Pain Relief Medications & Treatments
Best Acetaminophen
Best for Amazon Basic Care
Best for Caplet
Best for Back Pain
Best for Headache
Best for Muscle Pain
Best for Aspirin
Best for Ibuprofen
Amazon Basic Care Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, Pain Reliever/Fever Reducer, 500 Count
Amazon Basic Care
SB-123
3.0 x 3.0 x 5.7 Inches
0.7 Pounds
Ratings for Amazon Basic Care (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
Features
ACTIVE INGREDIENT: Amazon Basic Care Extra Strength Pain Relief's active ingredient is Acetaminophen, 500 mg, which compares to the active ingredient of Extra Strength Tylenol Caplets
Amazon Basic Care Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, temporarily relieves minor aches and pains due to: the common cold, headache, backache, minor pain of arthritis, toothache, muscular aches, and premenstrual and menstrual cramps also temporarily reduces fever
Top 10
Best OTC Medications & Treatments
Best Pain Relief Medications & Treatments
Best Acetaminophen
Best for Amazon Basic Care
Best for Tablet
Best for Back Pain
Best for Headache
Best for Muscle Pain
Best for Aspirin
Best for Ibuprofen
Amazon Basic Care Acetaminophen Extended-Release Tablets, 650 mg, Arthritis Pain, 400 Count
Amazon Basic Care
54479
3.06 x 3.06 x 5.5 inches
0.89 Pounds
Ratings for Amazon Basic Care (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
Features
ACTIVE INGREDIENT: Amazon Basic Care Acetaminophen Extended-Release Tablets, 650 mg active ingredient is acetaminophen 650 mg,. Compare to the active ingredient in Tylenol 8HR Arthritis Pain.
PURPOSE: Amazon Basic Care Acetaminophen Extended-Release Tablets, 650 mg is a pain reliever and fever reducer that can be used for the temporary relief of minor pain of arthritis.
Top 11
Best Ibuprofen
Amazon Basic Care Ibuprofen Tablets, 200 mg, Pain Reliever and Fever Reducer, For Arthritis, Toothache, Backache and More, 100 Count
Amazon Basic Care
1.78 x 3.44 x 1.78 inches
Ratings for Amazon Basic Care (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
Features
ACTIVE INGREDIENT: This pain reliever and fever reducer contains 200 mg of ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID); compare to Motrin IB active ingredient
RELIEF FOR ACHES AND PAINS: Amazon Basic Care Ibuprofen Tablets temporarily relieve minor aches and pains due to headache, muscular ache, minor pain of arthritis, toothache, backache, the common cold and menstrual cramps; also temporarily reduces fever
Top 12
Best for Tylenol
Best for Caplet
Best for Back Pain
Best for Muscle Pain
Best for Inflammation
Tylenol 8 Hour Arthritis Pain Relief Extended-Release Tablets, 650 mg Acetaminophen, Joint Pain Reliever & Fever Reducer Medicine, Oral Pain Reliever for Arthritis & Joint Pain, 225 Count
Tylenol
30045083837
0.12 x 5.0 x 5.0 Inches
0.1188 pounds
Ratings for Tylenol (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
Features
225 Count bottle of Tylenol 8 Hour Arthritis Pain Extended-Release Caplets with acetaminophen to provide fast-acting, temporary relief of minor arthritis and joint pain in hands, wrists, knees, ankles, elbows and feet
Each extended-release tablet contains 650 mg of acetaminophen, a known pain relieving and fever reducing ingredient, with two layers of effective pain relief - the first layer acts fast to relief joint pain, and the second lasts up to 8 hours
Top 13
Best Naproxen Sodium
Aleve Pain Relief Naproxen Sodium Caplets ‐ 50 Count
Aleve
1029464
2.5 x 2.06 x 3.97 inches
0.0875 pounds
Ratings for Aleve (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ❌ | ❌ | ❌ |
Features
Up to 12-Hours of Uninterrupted Pain Relief: Aleve Caplets provide long-lasting pain relief of minor arthritis, headache, and back pain
Fever Reducer: Temporarily reduces fever for adults and children aged 12 and up
Amazon Basic Care Ibuprofen Tablets 200 mg, Pain Reliever/Fever Reducer, Body Aches, Headache, Arthritis Relief and More, 500 Count
Amazon Basic Care
B074F297T8
3.0 x 3.0 x 4.75 inches
0.0006 Pounds
Ratings for Amazon Basic Care (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
Features
ACTIVE INGREDIENT: This product contains ibuprofen 200 mg, a pain reliever and fever reducer (NSAID); compare to the active ingredient in Advil Ibuprofen Tablets
PAIN RELIEVER AND FEVER REDUCER: Proven pain relief without a prescription for tough pain such as muscular aches, minor arthritis pain, toothache, backache, menstrual cramps or minor aches and pains from the common cold; also temporarily reduces fever
Amazon Basic Care Migraine Relief Geltabs, Acetaminophen, Aspirin (NSAID) and Caffeine, 80 Count
Amazon Basic Care
2.0 x 2.031 x 4.25 Inches
Ratings for Amazon Basic Care (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
Features
ACTIVE INGREDIENTS: This product contains acetaminophen 250 mg, aspirin 250 mg (NSAID: nonsteroidal anti-inflammatory drug) and caffeine 65 mg. Compare to the active ingredients of Excedrin Migraine Geltabs
PAIN RELIEF: Amazon Basic Care Migraine Relief Geltabs offer headache pain relief so you don't miss out on life's special moments
Top 16
Best Acetaminophen
Best for Amazon Basic Care
Best for Caplet
Best for Liquid
Best for Fever
Best for Headache
Best for Aspirin
Amazon Basic Care Rapid Release Acetaminophen Caplets 500 mg, Extra Strength Pain Reliever and Fever Reducer, 400 Count
Amazon Basic Care
W267
2.88 x 2.88 x 5.3 inches
0.7 Pounds
Ratings for Amazon Basic Care (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
Features
ACTIVE INGREDIENT: Amazon Basic Care Rapid Release Acetaminophen 500 mg Caplets active ingredient is 500 mg of acetaminophen, a pain reliever and fever reducer. Compare to Tylenol Extra Strength Rapid Release Gels active ingredient.
EFFECTIVE: This product temporarily relieves minor aches and pains due to headache, muscular aches, backache, minor pain of arthritis, the common cold, toothache and premenstrual and menstrual cramps. Also temporarily reduces fever.
Top 17
Best Ibuprofen
A+Health Mini Ibuprofen 200 Mg Softgels, Pain Reliever/Fever Reducer (NSAID), Made in USA, 500 Count
A+Health
IBU-MINI500
5.0 x 3.0 x 3.0 Inches
0.6 pounds
Ratings for A+Health (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
Features
25% SMALLER THAN REGULAR SOFTGELS: These Ibuprofen Mini Softgels are 25% smaller than our regular Ibuprofen Softgels, providing the same fast-acting relief while being easier for consumers to swallow
ACTIVE INGREDIENT IBUPROFEN 200MG: Contains active ingredient Ibuprofen 200mg (nonsteroidal anti-inflammatory drug)—compare to the active ingredient in Advil LIQUI-GELS Minis
Top 18
Best for Advil
Best for Caplet
Best for Back Pain
Best for Muscle Pain
Best for Inflammation
Best for Ibuprofen
Advil Dual Action Coated Caplets with Acetaminophen, 250 Mg Ibuprofen and 500 Mg Acetaminophen Per Dose (2 Dose Equivalent) for 8 Hour Pain Relief - 216 Count
Advil
F00573014786
2.7 x 4.7 x 4.7 inches
0.3307 Pounds
Ratings for Advil (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
Features
POWERFUL PAIN RELIEVER: Combination of acetaminophen 500mg and ibuprofen Per Dose (2 Dose Equivalent) for multi symptom pain relief
8 HOUR RELIEF: Pain relief pills that provide long-lasting, multi sympton pain relef for up to 8 hours. These powerful tablets relieve pain with ibuprofen to target pain at the source and acetaminophen to block pain signals.
Top 19
Best for Headache
NUVICARE Tension Headache Relief Pills with 500mg Acetaminophen and 65mg Caffeine - Non Aspirin Pain Reliever Aid - Compare to Active Ingredient in Aspirin Free Excedrin Tension Headache (2 Pack)
NUVICARE
Ratings for NUVICARE (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| NuviCare | - | ❌ | ❌ | ❌ |
Features
TARGETED RELIEF FOR TENSION HEADACHES - Don’t let the pressure and tightness in your head hold you back. With a combination of 500mg of acetaminophen and 65mg of caffeine, these tension headache pills work effectively to ease tension and give you the relief you need to power through.
COMPARE TO ACTIVE INGREDIENT IN EXCEDRIN - Our OTC tension headache medicine provides the same trusted active ingredients as major brands without the higher price tag. Formulated to target headaches fast with the same amount of acetaminophen (500 mg) and caffeine (65 mg).
GoodSense Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, 500 Count
GoodSense
3.064 x 3.064 x 5.75 inches
0.7 pounds
Ratings for GoodSense (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
Features
ACTIVE INGREDIENT: GoodSense Extra Strength Pain Relief's active ingredient is Acetaminophen, 500 mg, which compares to the active ingredient of Extra Strength Tylenol Caplets
GoodSense Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, temporarily relieves minor aches and pains due to: the common cold, headache, backache, minor pain of arthritis, toothache, muscular aches, and premenstrual and menstrual cramps. It also temporarily reduces fever
Top 21
Best OTC Medications & Treatments
Best Pain Relief Medications & Treatments
Best for Tylenol
Best for Caplet
Best for Headache
Best for Muscle Pain
Best for Aspirin
Best for Ibuprofen
Tylenol Extra Strength Pain Reliever and Fever Reducer Caplets, 500 mg Acetaminophen Pain Relief Pills for Headache, Backache, Toothache & Minor Arthritis Pain Relief; 100 ct.; Pack of 1
Tylenol
340200
3.8 x 2.0 x 2.0 Inches
0.025 Pounds
Ratings for Tylenol (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
Features
100-count of Tylenol Extra Strength Caplets with 500 mg of acetaminophen to provide temporary relief of minor aches and pains and help reduce fever
Each extra strength caplet contains 500 mg of acetaminophen for effective pain relief, and has an excellent safety profile when used as directed
HealthA2Z® Extra Strength Pain Relief PM| Acetaminophen 500mg | Diphenhydramine 25mg | Pain Reliever & Nighttime Sleep Aid | Non-Habit Forming (365 Count (Pack of 1))
HealthA2Z
FP0772
3.15 x 3.15 x 5.75 Inches
0.599 pounds
Ratings for HealthA2Z (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| HealthA2Z | 823 | ✅ | ✅ | ✅ |
Features
500 mg Acetaminophen, a proven pain reliever, helps relieve muscle, joint, headache, and arthritis pain quickly.
25 mg Diphenhydramine, a gentle, non-habit-forming sleep aid, helps you fall asleep and stay asleep while also relieving fever and minor aches and pain with the help of Acetaminophen.
Top 23
Best Pain Relief Medications & Treatments
Best Acetaminophen
Best for Tylenol
Best for Inflammation
Best for Aspirin
Tylenol Extra Strength Rapid Release Gels with Acetaminophen, Pain Reliever & Fever Reducer, 225 ct, 225 count
Tylenol
507156
2.44 x 5.5 x 2.44 inches
0.44 Pounds
Ratings for Tylenol (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
| ECOM EDGEZ INC | - | ❌ | ❌ | ❌ |
Features
225-count Tylenol Extra Strength Rapid Release Gels pain medicine with acetaminophen work fast to temporarily relieve minor aches and pains and help reduce fever
Each pain reliever gelcap features unique, laser-drilled holes to quickly release pain medicine and contains 500 mg of acetaminophen for fast, effective extra strength pain relief that works at the speed of life
Top 24
Best Naproxen Sodium
Aleve Arthritis Gelcap, Fast Acting All Day Pain Relief for Headaches, Muscle Aches, and Fever Reduction, Naproxen Sodium, 220 mg, Yellow, 160 Count
Aleve
3.07 x 3.07 x 5.75 inches
0.0005 pounds
Ratings for Aleve (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
Features
Just Two pills for all day pain relief. Each pill has the strength to last 12 hours.
Aleve's Triple Benefit: proven relief, all day long, with fewer pills. Each pill has the strength to last 12 hours. Based on minimum labeled dosage.
Top 25
Motrin Dual Action with Tylenol, Ibuprofen & Acetaminophen Fast-Acting, Long Lasting Pain Reliever for Minor Aches & Pains, Ibuprofen (NSAID) 125 mg & Acetaminophen 250 mg, 120 ct
Motrin
6.0 x 3.0 x 3.0 Inches
Ratings for Motrin (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ❌ | ❌ | ❌ |
Features
Dual Action Pain Reliever: One 120 count bottle of Motrin Dual Action with Tylenol, dual action ibuprofen (NSAID) and acetaminophen, pain reliever with two medicines for minor aches and pains
Acetaminophen and Ibuprofen: The dual action Motrin with Tylenol pain relief tablets each contain 250 mg acetaminophen plus 125 mg ibuprofen (nonsteroidal anti-inflammatory drug) to temporarily relieve minor aches and pains
Tylenol Children's Chewable, Grape, 24 Count
Tylenol
580828
2.05 x 2.85 x 2.0 Inches
0.05 pounds
Ratings for Tylenol (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
| QC_Wholesale | - | ✅ | ✅ | ✅ |
Features
24-count of Children's Tylenol Chewable Tablets with acetaminophen works to temporarily relieve minor aches and pains as well as cold and flu symptoms in children, including sore throat, headache and fever
This kids' cold & flu medicine helps relieve minor aches & pains including toothaches and headaches and temporarily reduces fever with an ibuprofen- and aspirin-free formula
Amazon Basic Care Naproxen Sodium Caplets 220 mg, Pain Reliever/Fever Reducer (NSAID), Muscular Aches, Backache, Headache, Toothache, Minor Arthritis Pain Relief and More, 300 Count
Amazon Basic Care
1
2.2 x 2.2 x 4.5 inches
0.2403 pounds
Ratings for Amazon Basic Care (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
Features
ACTIVE INGREDIENT: This pain reliever and fever reducer contains naproxen sodium 220 mg, a nonsteroidal anti-inflammatory drug (NSAID); compare to the active ingredient in Aleve Caplets
STRENGTH TO LAST 12 HOURS: Pain reliever and fever reduction for up to 12 hours so you can get through the day
Top 28
Best Ibuprofen
Advil Pain Reliever and Fever Reducer, Pain Relief Medicine with Ibuprofen 200mg for Headache, Backache, Menstrual Pain and Joint Pain Relief - 100 Coated Tablets
Advil
305730150408
3.95 x 2.0 x 1.94 Inches
0.05 Pounds
Ratings for Advil (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
Features
Box of tablets
Relieves aches and pains
GenCare - Tension Headache Relief Pain Reliever with Acetaminophen 500 mg and Caffeine 65 mg (200 Caplets) Value Pack | Extra Strength for Head and Body Aches
GenCare
0.3505 Pounds
Ratings for GenCare (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| GenCare Consumer Products, LLC | 8,741 | ✅ | ✅ | ✅ |
Features
✅ EXTRA STRENGTH RELIEF - Reach for GenCare extra strength Tension Headache Relief when suffering from mild to severe headaches, tension pain and muscle aches. Adults and children 12 and older take 2 caplets every 6 hours as needed with water.
✅ FULL BODY PAIN REMEDY - The potent combination of Acetaminophen (500mg) and Caffeine (65mg) isn't just for mild to severe headaches. It provides fast and effective relief for sore muscles, tooth aches, arthritis and joint pain.
Top 30
Best Acetaminophen
Best for Amazon Basic Care
Best for Box
Best for Packet
Best for Caplet
Best for Headache
Best for Aspirin
Best for Ibuprofen
Amazon Basic Care Extra Strength Acetaminophen Caplets 500 mg, Pain Reliever and Fever Reducer, Gentle on Stomach, For Arthritis Pain, Backache Pain and More, 50 Packets of 2 Capsules Each, 100 Count
Amazon Basic Care
3.25 x 4.25 x 4.75 Inches
0.19 Pounds
Ratings for Amazon Basic Care (CPR Score)
| Seller | CPR Rank | Amazon Fulfilled | Prime | Free Shipping |
|---|---|---|---|---|
| Amazon.com | - | ✅ | ✅ | ✅ |
Features
ACTIVE INGREDIENT: Amazon Basic Care Extra Strength Acetaminophen Caplets 500 mg's active ingredient is acetaminophen 500 mg. Compare to the active ingredient of Extra Strength Tylenol Caplets.
PAIN RELIEVER AND FEVER REDUCER: Temporarily relieves minor aches and pains due to: the common cold, headache, backache, minor pain of arthritis, toothache, muscular aches, and premenstrual and menstrual cramps Also temporarily reduces fever
Top 10 Non-aspirin Pain Relievers - Verified to Buy (August 2026)
- 1. Amazon Basic Care Extra Strength Pain Relief, Acetaminophen Caplets, 500...
- 2. Tylenol Extra Strength Acetaminophen Rapid Release Gels, Pain Reliever &...
- 3. Amazon Basic Care Extra Strength Pain Relief, Acetaminophen Caplets, 500...
- 4. Percogesic Extra Strength Pain Reliever, Aspirin Free, Dual Action Relief,...
- 5. Tylenol 8HR Arthritis Pain Relief Caplets, 650 mg Acetaminophen Pain...
- 6. Advil Dual Action Coated Caplets with Acetaminophen, 250 Mg Ibuprofen...
- 7. HealthA2Z® Pain Relief Extended Release | Acetaminophen 650mg | 8...
- 8. Amazon Basic Care Extra Strength Pain Relief, Acetaminophen Caplets, 500...
- 9. Amazon Basic Care Extra Strength Pain Relief, Acetaminophen Caplets, 500...
- 10. Amazon Basic Care Acetaminophen Extended-Release Tablets, 650 mg, Arthritis Pain,...
Top 10 Non-aspirin Pain Relievers Brands on Amazon
Here is the list of top-rated brands that were evaluated by CherryPicks.
- Amazon Basic Care
- Tylenol
- Percogesic
- Advil
- HealthA2Z
- Aleve
- A+Health
- NUVICARE
- GoodSense
- Motrin
Top 7 Non-aspirin Pain Relievers Sellers: CPR Seller Rank List
CPR sellers rank is based on CherryPicks-AI bestselling ranking system that helps us analyze each seller's sales trends. The List of top seller ranks is our in-house data, essential for our product ranking to help you make the right shopping choice.
- 1. HealthA2Z : 57,718 Yearly Feedback , Avg. Ratings 4.9
- 2. ISKOLIVE 12 INC : 27,651 Yearly Feedback , Avg. Ratings 4.8
- 3. GenCare Consumer Products, LLC : 7,768 Yearly Feedback , Avg. Ratings 4.9
- 4. ECOM EDGEZ INC : 931 Yearly Feedback , Avg. Ratings 4.9
- 5. QC_Wholesale : 615 Yearly Feedback , Avg. Ratings 4.6
- 6. Amazon.com : 386 Yearly Feedback , Avg. Ratings 4.7
- 7. EDEN TRADING : 70 Yearly Feedback , Avg. Ratings 3.3
| Rank | Name | Yearly Feedbacks | Avg. Ratings |
|---|---|---|---|
| 🥇 | HealthA2Z | 57,718 | 4.9 |
| 🥈 | ISKOLIVE 12 INC | 27,651 | 4.8 |
| 🥉 | GenCare Consumer Products, LLC | 7,768 | 4.9 |
| 4 | ECOM EDGEZ INC | 931 | 4.9 |
| 5 | QC_Wholesale | 615 | 4.6 |
| 6 | Amazon.com | 386 | 4.7 |
| 7 | EDEN TRADING | 70 | 3.3 |
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What does "Amazon Fulfilled" Mean?
Amazon Fulfilled refers to products handled by Amazon's logistics, which indicates that the product is stored, packed, and shipped by Amazon from one of its fulfillment centers.
When you order a product that is "Amazon Fulfilled," Amazon takes care of the storage, packing, shipping, and customer service for that product. This often ensures quicker delivery and better customer service compared to products that are not fulfilled by Amazon. It also means that the product is eligible for Amazon's return policy.
What does "Prime" Mean?
"Prime" refers to Amazon Prime Member (Join Amazon Prime Now), which indicates eligibility for Prime benefits. When you see "Prime" next to a product on Amazon, This generally means that if you are an Amazon Prime member, you can get free two-day shipping on that product, and sometimes even same-day or one-day shipping depending on your location.
Prime members also have access to other benefits, including 2-Day Shipping, Exclusive Member Deals, Prime Video, Buy With Prime, Amazon Music, Prime Gaming, and more.
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What does "Free Shipping" Mean?
"Free Shipping" means that you will not be charged additional fees for the shipping of that product. However, unlike "Prime," which usually guarantees fast two-day shipping, "Free Shipping" doesn't necessarily mean fast shipping.
Sometimes there might be a minimum purchase requirement to qualify for free shipping if you are not a Prime member. For Prime members, the "Free Shipping" usually refers to the free two-day shipping that is one of the benefits of the Prime membership.
Why Should You Trust Us?
Now hundreds and thousands of Health Care supplies are available on Amazon, Picking the right one is not easy, and that may take a lot of your time, Right? and What is the best Non-aspirin Pain Relievers to buy for new August 2026?
CherryPicks’s Methodology for Evaluating Non-aspirin Pain Relievers
We developed the CherryRatings-AI system to identify and score reviews and the CherryPicks-AI ranking system that uses TensorFlow framework to generate the best list, It will help us evaluate Health Care items that sell on Amazon. The score of items is based on over ten parameters such as analyzing customer review content, product reviewing rating statistics, brand reputation evaluation, comparing product price with features, etc, You can visit How We Rank to learn more in detail.
We collected and analyzed 306 of Non-aspirin Pain Relievers reviews based on our selection criteria. It helped us shortlist the top qualified and rated Non-aspirin Pain Relievers for Health Care, We found that most customers choose Non-aspirin Pain Relievers with an average price of $13.12, and the top brands are Amazon Basic Care, Tylenol, HealthA2Z, GoodSense, Advil, Motrin, Aleve And Percogesic.
Then our expert-level editors reviewed all those quality items and selected the top 30 Non-aspirin Pain Relievers for you, We have researched hundreds of sellers and picked the top sellers for Health Care, including HealthA2Z, ISKOLIVE 12 INC, GenCare Consumer Products, LLC, ECOM EDGEZ INC, QC_Wholesale, Amazon.com And EDEN TRADING. The Amazon Basic Care Extra Strength Pain Relief, A... are available for purchase right now, and The seller of #1 rank product has received honest feedback from 4,001 consumers with an average rating of 4.8.
We've helped a lot of satisfied users get the right Health & Household product based on their needs, and save lots of time for them to pick Non-aspirin Pain Relievers to buy.
Daniel is a part-time writer on the platform as he has got a full-time job as a practicing medical doctor. When he is free, he share with us, his knowledge about health and well being. He is your plug if you are interested in healthy living habits.