Best Moisturizing Eye Drops (Sep. 2026) - Rated by CherryPicks' Experts

At a Glance: Our Top Picks

Top 1

Systane Long Lasting Lubricant Eye Drops, 1 Fl. Oz (Pack of 1)

9.8
CPR Score
Top 2

Systane Ultra Lubricant Eye Drops,0.14 Fl Oz (Pack of 1)

9.7
CPR Score
Top 3

Refresh Plus Lubricant Eye Drops, Value Size, 70-0.01 Fluid Ounce (0.4 ml) Co...

9.6
CPR Score
Tips


Our team has selected the top 30 best Moisturizing Eye Drops by analyzing and evaluating 231 products of different Health Care brands, including BLINK, Refresh, Systane, Biotrue, Visine, Genteal And Soothe, Still, Our editor rated and compared them on product features before you buy.

* CherryPicks.Reviews is reader-supported, Our editor review, and recommend the best products based on extensive data analysis, if you click on the product links, we may earn a commission through qualifying products purchased.

Market Overview
Moisturizing Eye Drops Reviewed
  • Reviews Analyzed: 233,311 Items
  • CPR Avg. Rating: 8.5 / 10
30 Products Evaluated
  • Highest Price: $40.00
  • Lowest Price: $4.25
  • Avg. Price: $16.18
  • Price Disclaimer

Top 30 Moisturizing Eye Drops on Amazon (Verified You can Buy)

Systane Long Lasting Lubricant Eye Drops, 1 Fl. Oz (Pack of 1)

Systane
0065042930
1.5 x 1.0 x 1.0 inches
0.0625 Pounds

Ratings for Systane (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -
greenbuyss -
bigappletrading -

Features

Eyes feel moist and refreshed longer
Lasting relief; soothing comfort
Show More

Systane Ultra Lubricant Eye Drops,0.14 Fl Oz (Pack of 1)

Systane
0065143131
1.28 x 1.78 x 3.31 inches
0.0088 Pounds

Ratings for Systane (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -

Features

Dr Recommended Brand of Artificial Tears
Extended Protection
Show More

Refresh Plus Lubricant Eye Drops, Value Size, 70-0.01 Fluid Ounce (0.4 ml) Containers

Refresh
403702
3.75 x 7.0 x 4.0 inches
0.25 pounds

Ratings for Refresh (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Cygnet Online -
Amazon.com -

Features

Original strength, preservative-free formula
Relieves mild symptoms of eye dryness
Show More

BLINK Triple Care Eye Drops for Dry Eyes, Lubricant Eye Drops, Soothing for Moderate to Severe Dry Eyes, with Hyaluronate, Reduces Discomfort, Long-Lasting Hydration, 0.34 Fl Oz

BLINK
EM1664595
1.3 x 0.79 x 4.08 inches

Ratings for BLINK (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -

Features

Relief with every Blink: Experience extended dry eye symptom relief with Blink Triple Care Lubricating Eye Drops. This 3-in-1 formula instantly soothes, gives extra long-lasting hydration, and seals in moisture.
Dry Eye Lubricant: Discover what makes Blink Triple Care Lubricating Eye Drops different from other eye drops. Our drops for dry eyes have a dual-action moisture seal to lock in moisture for instant, long-lasting relief. The secret to our drops is a water-based formula enhanced with natural oil, which helps keep tears from evaporating too quickly
Show More

Systane Ultra Lubricant Eye Drops, Artificial Tears for Dry Eye, Twin Pack, 10-mL Each

Systane
0065143141p
6.0 x 5.0 x 4.0 inches
0.0875 pounds

Ratings for Systane (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -
Voxtel -
barginhousedeals -
EvergreenCreations -

Features

#1 Dr Recommended Brand of Artificial Tears*, packaging may vary
Extended Protection
Show More

Refresh Optive Advanced Eye Drops, 0.33 Fl Oz (Pack of 2)(Twin Pack)

Refresh
94771
1.26 x 2.2 x 3.81 inches
0.0429 pounds

Ratings for Refresh (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Active Trade 6,587
Amazon.com -
Premium Household 3,184
greenbuyss -

Features

Triple-action relief drop
Lubricants and hydrates dry, burning, irritated eyes
Show More

Biotrue Hydration Boost Drops, Soft Contact Lens Friendly for Irritated and Dry Eyes from Bausch + Lomb, Preservative Free, Naturally Inspired, 0.33 FL OZ (10 mL), Pack of 2

Biotrue

Ratings for Biotrue (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -
EvergreenCreations -
Stam Sales 1,941
Bor312 -

Features

NATURALLY INSPIRED INGREDIENTS: Biotrue Hydration Boost Eye Drops are enhanced with HA (Hyaluronan), Antioxidant, and Electrolyte and provide instant moisture for dry eyes.
CONTACT LENS FRIENDLY: Biotrue Hydration Boost Eye Drops can be applied while wearing soft contact lenses.
Show More

Biotrue Hydration Boost Eye Drops, Preservative Free, Soft Contact Lens Friendly for Irritated and Dry Eyes from Bausch + Lomb, Naturally Inspired, 0.33 FL OZ (10 mL)

Biotrue
BA622278
1.75 x 1.07 x 3.38 inches

Ratings for Biotrue (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -
EvergreenCreations -

Features

NATURALLY INSPIRED INGREDIENTS: Biotrue Hydration Boost Eye Drops are enhanced with HA (Hyaluronan), Antioxidant, and Electrolyte and provide instant moisture for dry eyes.
CONTACT LENS FRIENDLY: Biotrue Hydration Boost Eye Drops can be applied while wearing soft contact lenses.
Show More

Soothe XP Eye Drops by Bausch Lomb, Lubricant Relief for Dry Eyes, 15 mL

Soothe
AB49311
2.31 x 1.38 x 3.75 Inches

Ratings for Soothe (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
DeRomo -
Amazon.com -

Features

EXTRA PROTECTION FOR DRY EYES: Soothe XP Eye Drops do what ordinary eye drops (non-lipid containing) can't The Soothe XP formula helps restore the eyes lipid layer for relief that lasts
DIFFERENT THAN ARTIFICIAL TEARS: MGD, which often includes breakdown of the lipid layer, is the main cause of evaporative dry eye Soothe XP Dry Eye Drops help restore the lipid layer to seal in moisture & protect against further irritation
Show More

Systane Balance Lubricant Eye Drops, Restorative Formula, Twin pack, 0.33 Fl Oz (Pack of 2)

Systane
B010CQVOEM
1.28 x 2.59 x 4.31 inches
0.07 pounds

Ratings for Systane (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
sweeteddy -
Amazon.com -
EvergreenCreations -
Bronzewit Central -
ECB Logistics -
Healthi Solutions -
greenbuyss -

Features

Clinical strength intensive therapy
Restorative formula
Show More

Blink Boost Preservative-Free Lubricating Eye Drops, Moisturizing & Soothing for Mild Dry Eyes, with Hyaluronate, Hydrating Relief Instant Comfort Throughout the Day, Contact Lens Friendly, 0.34 FL Oz

BLINK
4.17 x 1.81 x 1.26 Inches
0.04 Pounds

Ratings for BLINK (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -

Features

Preservative-Free Formula: Blink Boost Lubricating Eye Drops provide fast-acting relief from dryness and discomfort. The preservative-free formula is pH balanced to mimic natural tears, offering extra hydration and helps relieve dry eyes
Advanced Long-Lasting Hydration: Infused with hyaluronan, an electrolyte, and an antioxidant, these dry eyes eye drops enhance moisture retention while relieving discomfort from irritants like wind or sun, & provides comfort throughout the day
Show More

Refresh Digital PF Lubricant Eye Drops, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 30 Count (Pack of 1)

Refresh
2.0 x 3.0 x 4.0 Inches
0.0195 pounds

Ratings for Refresh (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -

Features

Preservative-free formula acts fast to relieve dryness, burning, irritation, and discomfort in the eyes that may be due to digital device use
Delivers soothing hydration by supporting all three tear film layers
Show More

Refresh Optive Gel Drops Lubricant Eye Gel, 0.33 Fl Oz (Pack of 1) Sterile, Packaging May Vary

Refresh
95459
1.13 x 1.75 x 3.5 Inches
0.0213 pounds

Ratings for Refresh (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -
Hollywoodseller -

Features

Extended relief plus protection for dry, irritated eyes
Our most comprehensive gel formula
Show More

Refresh Relieva Preservative-Free Lubricant Eye Drops, 0.33 Fl Oz (Pack of 1), Packaging May Vary

Refresh
50300236634105
1.72 x 1.68 x 3.98 inches
0.0215 Pounds

Ratings for Refresh (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -
Smart Wellness -
Redmi a -

Features

Innovative, preservative-free formula in a multidose bottle
Relieves discomfort due to dry, irritated eyes
Show More

Refresh Optive Lubricant Eye Drops, Sterile, 0.5 Fl. Oz (Pack of 1)

Refresh
93241
3.55 x 1.8 x 1.2 inches
0.0313 Pounds

Ratings for Refresh (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -
JL6SBL -
Bronzewit Central -

Features

Dual-action formula lubricates and hydrates
Relieves mild symptoms of eye dryness
Show More

Oasis TEARS PF Preservative-Free Lubricant Eye Drops Relief for Dry Eyes, 0.34 Ounce

Oasis TEARS
OT6400
2.6 x 0.8 x 2.6 inches
0.0438 pounds

Ratings for Oasis TEARS (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Healthy Eyes -
DS Health & Beauty -
EyeCare&More -
VerSure 157
Plush Eyes -
OASIS Medical Inc. -

Features

Oasis TEARS PF Preservative-Free Lubricant Eye Drops Relief For Dry Eyes, 0.34

Splash Tears, Lubricant Eye Drops for Dry Eyes, Fast Acting and Long Lasting Formula, Relieves Dryness, Grittiness, and Irritation, Moisturizing Eye Drops, Eye Care for Dry Eyes, 0.5 FL Oz, Bottle

SPLASH TEARS
FETEGT1561
1.1 x 1.85 x 3.7 inches
0.0313 pounds

Ratings for SPLASH TEARS (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -

Features

Splash Tears Lubricant Eye Drops for Dry Eyes is fast-acting and long-lasting, providing relief from dryness, grittiness, and irritation.
Splash Tears dry eye drops are essential when you are exposed to wind, sun, air conditioning, and/or using cellphones and computers for too long.
Show More

Refresh Relieva PF Lubricant Eye Drops, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 30 Count

Refresh
AL94515
2.0 x 3.0 x 4.0 inches
0.0006 pounds

Ratings for Refresh (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -

Features

Preservative free formula relieves discomfort due to dry, irritated eyes
Prevents further irritation
Show More

Systane COMPLETE PF Multi-Dose Preservative Free Dry Eye Drops 20ml(Pack of 2 – 10mL bottles) (Packaging may vary)

Systane
1.22 x 2.68 x 4.45 inches
0.044 pounds

Ratings for Systane (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -
greenbuyss -

Features

Fast acting hydration for sensitive eyes
Preservative free tear evaporation protection
Show More

Refresh Relieva Lubricant Eye Drops For Dry Eyes, 0.33 Fl Oz Sterile

Refresh
3010
1.13 x 1.75 x 3.5 inches
0.04 Pounds

Ratings for Refresh (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -

Features

Innovative formula relieves discomfort due to dry, irritated eyes
Prevents further irritation
Show More

GenTeal Tears Lubricant Eye Drops, Moderate Liquid Drops, Twin Pack ,0.5 Fl Oz (Pack of 2) Package May Vary

Genteal
0065042637
1.25 x 2.56 x 4.25 inches
0.0313 pounds

Ratings for Genteal (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -

Features

Moderate Dry Eye Symptom Relief
Fast Soothing Relief
Show More

Biotrue Hydration Boost for Contacts, Rehydrating Eye Drops for Dry Eyes, Preservative Free, Refreshes, Lubricates & Moisturizes Lenses, Rewetting Eye Drops, 0.33 FL Oz (Pack of 1)

Biotrue
BA622249
1.0709 x 1.752 x 3.3858 inches

Ratings for Biotrue (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -

Features

NATURALLY INSPIRED INGREDIENTS: Biotrue Hydration Boost for Contacts are enhanced with HA (Hyaluronan), Antioxidant (Protects HA from free radicals), and Electrolyte.
LASTING MOISTURE: For up to 8 hours of moisture (based on a laboratory study) and to help prevent deposit buildup.
Show More

Refresh Plus Lubricant Eye Drops, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 50 Count, Packaging May Vary

Refresh
5783
5.0 x 5.0 x 5.0 inches
0.0006 Pounds

Ratings for Refresh (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -

Features

Original strength, preservative-free formula
Relieves mild symptoms of eye dryness
Show More

Systane Lubricant Eye Gel Drops, 10-mL (Packaging May Vary)

Systane
0065045407
1.25 x 1.76 x 3.86 inches
0.051 Pounds

Ratings for Systane (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
barginhousedeals -
Amazon.com -
Bronzewit Central -
greenbuyss -
bigappletrading -

Features

#1 Dr Recommended Brand of Artificial Tears*
Thicker eye drop formulation that creates a protective shield over your eyes.
Show More

Refresh OPTIVE MEGA-3 PF Lubricant Eye Drops Preservative-Free Artificial Tears, 0.33 fl oz (10mL)

Refresh

Ratings for Refresh (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -

Features

FAST ACTING: Rapid relief to comfort dry, irritated eyes
LASTING RELIEF: One drop provides 10+ hours of dry eye relief (results may vary) (Data on file, AbbVie, Inc. REF-136415)
Show More

Visine Red Eye Hydrating Comfort Redness Relief and Lubricant Eye Drops to Help Moisturize and Relieve Red Eyes Due to Minor Eye Irritations Fast, Tetrahydrozoline HCl, 0.5 fl. oz

Visine
1.07 x 1.76 x 3.75 inches
0.06 Pounds

Ratings for Visine (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -

Features

0.5-fluid ounce bottle of Visine Red Eye Hydrating Comfort Redness Relief Eye Drops to offer eye redness relief in 30 seconds and lubricate irritated eyes
Formula contains 1% polyethylene glycol 400 and 0.05% tetrahydrozoline HCl which helps lubricate, refresh and relieve red irritated eyes
Show More

Blink® Tears Lubricating Eye Drops 1 fl oz (30 mL)

BLINK
93408
1.26 x 2.08 x 4.27 inches
0.04 pounds

Ratings for BLINK (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Thrifty White Health Essentials 1,442
Lone Mountain Books -
Honey Hill Market -
OTC Drugstore Online -
OTCRx4u 233
Bor312 -
Amazon.com -

Features

Relief with every Blink
For mild moderate dry eye
Show More

Systane Ultra Preservative Free Lubricant Eye Drops, 0.34 fl oz, Fast-Acting Dry Eye Relief from Irritation & Dryness, Hydrating Eye Drops for Extended Protection, Multi-Dose Bottle

Systane
0.0397 pounds

Ratings for Systane (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
greenbuyss -
SellerBetter-Inc -
Amazon.com -
bigappletrading -

Features

Fast-Acting Dry Eye Relief for Dry, Irritated Eyes: Systane ULTRA Preservative-Free Lubricant Eye Drops provide rapid hydration and lasting relief for dry eyes caused by irritants like screen time, air quality, low humidity, or seasonal changes. Designed for occasional or mild dry eye sufferers
Targets the Aqueous Layer: Formulated with Polyethylene Glycol 400 and Propylene Glycol, our moisturizing eye drops for dry eyes help hydrate and protect the ocular surface by replenishing the aqueous (water) layer of the tear film to deliver fast-acting and long-lasting dry eye relief throughout the day
Show More

Blink Tears Lubricating Mild-Moderate Dry Eye Drops, 0.5 Fluid Ounce

BLINK
131870
1.26 x 1.75 x 4.03 inches
0.065 Pounds

Ratings for BLINK (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
THE DRUG-DEPOT -
Bor312 -
Pharmapacks_ 5
H.M. Chicago -
JDC WHOLESALE -
G5Supply -
Amazon.com -

Features

Blink tears lubricating eye drops mild-moderate dry eye 0.5 fl oz
This product made of high quality material
Show More

Refresh Optive Mega-3 Lubricant Eye Drops, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 60 Count

Refresh
4.0 x 3.0 x 4.75 Inches
0.243 pounds

Ratings for Refresh (CPR Score)

Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -
Healthi Solutions -
ecompare -

Features

The only drop with omega-3s from flaxseed oil
Treats the signs and symptoms of Dry Eye associated with Meibomian Gland Dysfunction (MGD)
Show More

Top 10 Moisturizing Eye Drops - Verified to Buy (September 2026)

Top 9 Moisturizing Eye Drops Brands on Amazon

Here is the list of top-rated brands that were evaluated by CherryPicks.

  • Systane
  • Refresh
  • BLINK
  • Biotrue
  • Soothe
  • Oasis TEARS
  • SPLASH TEARS
  • Genteal
  • Visine

Specific Moisturizing Eye Drops Guides

For more personalized Moisturizing Eye Drops guides to match your different needs, check out the following pages,


Top 10 Moisturizing Eye Drops Sellers: CPR Seller Rank List

CPR sellers rank is based on CherryPicks-AI bestselling ranking system that helps us analyze each seller's sales trends. The List of top seller ranks is our in-house data, essential for our product ranking to help you make the right shopping choice.

Rank Name Yearly Feedbacks Avg. Ratings
🥇 Pharmapacks_ 1,218,675 4.8
🥈 VerSure 210,352 4.9
🥉 OTCRx4u 155,703 4.7
4 Stam Sales 29,951 4.9
5 Premium Household 19,545 4.8
6 Active Trade 10,160 4.9
7 JL6SBL 5,367 4.9
8 Hollywoodseller 4,914 4.9
9 DeRomo 4,116 4.9
10 EvergreenCreations 3,841 4.9
View or download top Moisturizing Eye Drops seller & rating report
Pharmapacks_ [1218675] VerSure [210352] OTCRx4u [155703] Stam Sales [29951] Premium Household [19545] Active Trade [10160] JL6SBL [5367] Hollywoodseller [4914] DeRomo [4116] EvergreenCreations [3841] Pharmapacks_ 73% VerSure 13% OTCRx4u 9% Stam Sales 2% Premium Household 1% Active Trade 1% JL6SBL 0% Hollywoodseller 0% DeRomo 0% EvergreenCreations 0%

[Get] Moisturizing Eye Drops Deals (✅Exclusively for Prime)

What does "Amazon Fulfilled" Mean?

Amazon Fulfilled refers to products handled by Amazon's logistics, which indicates that the product is stored, packed, and shipped by Amazon from one of its fulfillment centers.

When you order a product that is "Amazon Fulfilled," Amazon takes care of the storage, packing, shipping, and customer service for that product. This often ensures quicker delivery and better customer service compared to products that are not fulfilled by Amazon. It also means that the product is eligible for Amazon's return policy.

What does "Prime" Mean?

"Prime" refers to Amazon Prime Member (Join Amazon Prime Now), which indicates eligibility for Prime benefits. When you see "Prime" next to a product on Amazon, This generally means that if you are  an Amazon Prime member, you can get free two-day shipping on that product, and sometimes even same-day or one-day shipping depending on your location.

Prime members also have access to other benefits, including 2-Day ShippingExclusive Member DealsPrime VideoBuy With PrimeAmazon MusicPrime Gaming, and more.

Shop Prime Moisturizing Eye Drops Deals

What does "Free Shipping" Mean?

"Free Shipping" means that you will not be charged additional fees for the shipping of that product. However, unlike "Prime," which usually guarantees fast two-day shipping, "Free Shipping" doesn't necessarily mean fast shipping.

Sometimes there might be a minimum purchase requirement to qualify for free shipping if you are not a Prime member. For Prime members, the "Free Shipping" usually refers to the free two-day shipping that is one of the benefits of the Prime membership.


Why Should You Trust Us?

Now hundreds and thousands of Health Care supplies are available on Amazon, Picking the right one is not easy, and that may take a lot of your time, Right? and What is the best Moisturizing Eye Drops to buy for new September 2026?

CherryPicks’s Methodology for Evaluating Moisturizing Eye Drops

We developed the CherryRatings-AI system to identify and score reviews and the CherryPicks-AI ranking system that uses TensorFlow framework to generate the best list, It will help us evaluate Health Care items that sell on Amazon. The score of items is based on over ten parameters such as analyzing customer review content, product reviewing rating statistics, brand reputation evaluation, comparing product price with features, etc, You can visit How We Rank to learn more in detail.

We collected and analyzed 231 of Moisturizing Eye Drops reviews based on our selection criteria. It helped us shortlist the top qualified and rated Moisturizing Eye Drops for Health Care, We found that most customers choose Moisturizing Eye Drops with an average price of $16.16, and the top brands are BLINK, Refresh, Systane, Biotrue, Visine, Genteal And Soothe

Then our expert-level editors reviewed all those quality items and selected the top 30 Moisturizing Eye Drops for you, We have researched hundreds of sellers and picked the top sellers for Health Care, including Pharmapacks_, VerSure, OTCRx4u, Stam Sales, Premium Household, Active Trade, JL6SBL, Hollywoodseller, DeRomo, EvergreenCreations, Bronzewit Central And Plush Eyes. The Systane Long Lasting Lubricant Eye Drops, 1 Fl.... are available for purchase right now, and The seller of #1 rank product has received honest feedback from 9,060 consumers with an average rating of 4.8.

We've helped a lot of satisfied users get the right Health & Household product based on their needs, and save lots of time for them to pick Moisturizing Eye Drops to buy.


Written By Carolina James

Carolina is a student nutritionist that have a thing for writing about health, nutrition and how to stay and live healthy. She does not only provide us tips and tricks, she also review products she comes across that would help us to achieve the level of wellness we seek.