Best DGL Supplements (Aug. 2026) - Rated by CherryPicks' Experts

Ultimate Guide to DGL Supplements: Benefits, Dosage, and Top Picks!

DGL (Deglycyrrhizinated Licorice) supplements are derived from licorice root and are primarily used to promote gastrointestinal health and soothe digestive discomfort. They are commonly used to support the treatment of gastric ulcers and acid reflux (GERD). DGL works differently from antacids and H2-receptor antagonists, which focus on reducing gastric acidity. Instead, DGL promotes the production of mucus that protects the stomach lining.

Studies have shown that DGL can be effective in treating gastric ulcers and may help prevent ulcers in patients requiring long-term treatment with ulcerogenic drugs such as aspirin, nonsteroidal anti-inflammatory agents, and corticosteroids. DGL is available in various forms, including chewable tablets, capsules, and powders..

Benefits of DGL Supplements

The primary benefits of DGL supplements include:

• Promoting Gastrointestinal Health: DGL is known for its soothing effect on the gastrointestinal tract. It helps in maintaining a healthy lining of the esophagus and stomach, which is crucial for overall digestive health.
• Soothing Digestive Discomfort: Individuals suffering from minor digestive discomforts, such as bloating or stomach pain, may find relief through the use of DGL supplements. The soothing properties of DGL can help alleviate these symptoms.
• Support in Treating Gastric Ulcers: DGL has been commonly used in the support and treatment of gastric ulcers. It aids in the healing process by promoting the production of mucus, which acts as a protective barrier for the stomach lining against stomach acids.
• Managing Acid Reflux (GERD): For those suffering from acid reflux or gastroesophageal reflux disease (GERD), DGL can provide relief. It helps by coating and protecting the esophageal lining, thus reducing irritation caused by stomach acids.
• Stimulating Mucus Production: DGL is effective in promoting the production of mucus in the digestive tract. This mucus plays a crucial role in protecting the stomach lining from acidic damage and enzymatic erosion, thereby aiding in maintaining a healthy digestive system.

It's important to note that while DGL supplements offer these benefits, they should be used as part of a broader approach to managing digestive health, which may include diet changes, stress management, and other treatments as recommended by a healthcare professional. 

DGL Supplements Facts and Trends

The rising interest in DGL (Deglycyrrhizinated Licorice) supplements is part of a larger trend focusing on gut health. This trend is evident in the popularity of DGL-related content on social media, with over 27 million views on TikTok videos, and the commercial success of DGL products, such as a chewable tablet brand earning approximately $64K monthly on Amazon. 

Approximately 70 million Americans face digestive issues, contributing to the growing online and commercial interest in gut health supplements. This is highlighted by the massive 6.5 billion views for gut health videos on TikTok and a 186% increase in searches for “gut supplement” over five years.

Alongside DGL, L-glutamine supplements are also trending, with search interest growing by 720% in 24 months and top-selling products like L-glutamine powder generating about $180K monthly on Amazon. This indicates a significant consumer shift towards natural supplements for gut health maintenance.

Factors to Choosing the Best DGL Supplements

When selecting the best DGL (Deglycyrrhizinated Licorice) supplements, it's crucial to consider a range of factors to ensure you're choosing a high-quality product that aligns with your health needs. Here's a detailed guide to help you make an informed decision:

Understanding DGL:

DGL is a form of licorice root with the glycyrrhizin compound removed to prevent side effects like high blood pressure and water retention. It's primarily used for treating digestive issues such as acid reflux and ulcers.

Form of Supplement:

DGL supplements are available in chewable tablets, capsules, powders, and liquids. Chewable tablets are popular as saliva can enhance the effectiveness of DGL. Choose a form that suits your lifestyle and preferences.

Dosage and Concentration:

The typical dosage for DGL ranges between 250 and 500 mg, taken 15-30 minutes before meals. Ensure the product provides an adequate amount of DGL for efficacy. Standard advice suggests two to four 380-mg chewable tablets before meals.

Ingredients and Purity:

Opt for supplements with minimal additional ingredients and avoid unnecessary fillers, artificial flavors, or sweeteners. Some supplements include beneficial ingredients like aloe vera or slippery elm for added digestive support. Check if the supplement is free from additives like fillers, binders, and artificial colors or flavors.

Quality and Manufacturing Standards:

Select products from reputable brands manufactured in GMP-certified facilities. This certification ensures adherence to strict quality standards. Customer reviews can also offer insights into a product’s effectiveness and quality.

Allergen Information:

If you have allergies, carefully read the product label. Some DGL supplements may contain common allergens such as soy, gluten, or dairy.

Special Dietary Needs:

If you adhere to specific dietary restrictions like vegan or kosher diets, ensure the DGL supplement meets these requirements.

Additional Ingredients:

Some DGL supplements may include digestive enzymes or probiotics, enhancing their effectiveness. Consider if these additional ingredients align with your health goals.

Price:

Compare prices to find a product that offers good value but doesn't compromise quality for cost. Higher-priced options may offer better quality or additional beneficial ingredients.

Remember, while DGL supplements are generally safe, they're not a substitute for medical treatment. They should be part of an overall health plan that includes diet, lifestyle changes, and, where necessary, medication.

Round Up of the Best DGL Supplements (Verified to Buy)

• 1. Pure Encapsulations DGL Plus - Gut Health Supplements for Men...
• 2. WDVNEX DGL Gummies, 400 Mg DGL Extract Supplement, with Licorice...
• 3. DGL Gummies | Deglycyrrhizinated Licorice Root Extract, Quercetin, Aloe Vera,...
• 4. Planetary Herbals DGL Licorice Tablets, 100 Count
• 5. IIEltruiom DGL Gummies | Deglycyrrhizinated Licorice Root Extract, Zinc L-Carnosine,...
• 6. Nutricost DGL Deglycyrrhizinated Licorice Extract 120 Capsules for 120 Servings...
• 7. Carlyle DGL | 200 Capsules | Deglycyrrhizinated Licorice | Vegetarian,...
• 8. Designs for Health Deglycyrrhizinated Licorice Root Chewables - DGL Synergy...
• 9. FITO MEDIC'S Lab | Licorice Root |180 Capsules |Licorice Root...
• 10. DGL Licorice Supplement: Supports Digestive Health, Gut Lining Support, DGL...

Top 10 DGL Supplements Brands on Amazon

Here is the list of top-rated brands that were evaluated by CherryPicks.

• Pure Encapsulations
• WDVNEX
• Blltzzz
• Planetary Herbals
• IIEltruiom
• Nutricost
• Carlyle
• Designs for Health
• FITO MEDIC'S
• Kidney Restore

Specific DGL Supplements Guides

For more personalized DGL Supplements guides to match for your different needs, check out the following pages,

DGL Supplements FAQs

What Side Effects Might Occur with DGL Licorice Use?

Deglycyrrhizinated licorice (DGL) is a form of licorice that has had glycyrrhizin removed, which is the component that can cause serious side effects such as high blood pressure, headaches, and heart problems. Therefore, DGL is generally considered to have fewer side effects than regular licorice. However, it may still pose certain health risks. Some people may experience allergic reactions to DGL, especially if they have known allergies to other plants in the Fabaceae family, also known as the pea or legume family.

Symptoms of an allergic reaction can include hives or rash, swelling of the extremities or tongue, and difficulty breathing. Additionally, DGL may have hormonal effects, behaving like adrenal hormones such as estrogen and testosterone in the body. Therefore, it should be avoided by women with hormone-driven conditions and by men with low testosterone levels.

Can DGL Effectively Alleviate Symptoms of Acid Reflux?

Yes, DGL has been shown to be effective in treating conditions like acid reflux or gastroesophageal reflux disease (GERD). It is often used as a natural remedy for these conditions and has been found to work well for many patients. DGL can help soothe the stomach and esophagus, reducing the symptoms of heartburn and indigestion.

Is It Safe to Use DGL Continuously Over an Extended Period?

While DGL is generally considered safe to use, it should not be used for a long period without medical supervision. Even though DGL has glycyrrhizin removed, which is the component that can cause serious side effects, it may still pose certain health risks. For example, it should be avoided by people with a history of diabetes, edema, high blood pressure, or heart, kidney, or liver disease. Furthermore, DGL may reduce the effectiveness of hormone replacement therapy and birth control pills due to its potential hormonal effects.

What Is the Recommended Daily Dosage for DGL?

The standard dosage for DGL is two to four 380-mg chewable tablets taken between or 20 minutes before meals. However, the exact dosage may vary depending on the individual's health condition and the specific product used. Therefore, it's important to follow the instructions on the product label or consult with a healthcare provider to determine the appropriate dosage.

Are DGL Capsules an Effective Form of This Supplement?

Yes, DGL capsules can be effective for certain conditions. Many users have reported positive effects from using DGL capsules, particularly for digestive issues like acid reflux or GERD. However, the effectiveness of DGL can vary from person to person, and it's important to note that while DGL can help manage symptoms, it may not cure underlying conditions. As with any supplement, it's recommended to consult with a healthcare provider before starting to use DGL capsules.

How Long Does It Take for DGL Licorice to Work？

The time it takes for DGL to work can vary depending on the individual and the condition being treated. However, in a study where patients received DGL for ulcerative conditions, substantial improvement was usually observed within 5 to 7 days. It's important to note that while DGL can help manage symptoms, it may not cure underlying conditions. 

Top 10 DGL Supplements Sellers: CPR Seller Rank List

CPR sellers rank is based on CherryPicks-AI bestselling ranking system that helps us analyze each seller's sales trends. The List of top seller ranks is our in-house data, essential for our product ranking to help you make the right shopping choice.