Prilosec Buying Guide & Brand Review (Sep. 2026 Updated)

At a Glance: Top Prilosec Picks

Top 1

Prilosec OTC, Omeprazole 20mg, Heartburn Medicine, Acid Reflux Medicine, 24 H...

Top 2

Prilosec OTC Frequent Heartburn Medicine and Acid Reducer Tablets 42 Count - ...

Top 3

Prilosec OTC, Omeprazole Delayed Release 20mg, Acid Reducer, Treats Frequent ...

* CherryPicks.Reviews is reader-supported, Our editor review, and recommend the best products based on extensive data analysis, if you click on the product links, we may earn a commission through qualifying products purchased.

Market Overview
Prilosec Reviewed
  • Reviews Analyzed: 37,999 Items
  • CPR Avg. Rating: 9.2 / 10
37 Products Evaluated
  • Highest Price: $204.86
  • Lowest Price: $9.97
  • Avg. Price: $33.65
Price Disclaimer

Top 15 Prilosec Products On Amazon (Verified to buy)

Prilosec OTC, Omeprazole 20mg, Heartburn Medicine, Acid Reflux Medicine, 24 Hour Relief, 42 Tablets

Prilosec
OTC
2.32 x 4.75 x 3.7 inches
0.03 Pounds
Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -

Features

TREATS FREQUENT HEARTBURN: Heartburn medicine for those who experience heartburn flare ups 2+ times a week
With 1 PRILOSEC OTC PILL EACH MORNING, 24 HOURS. ZERO HEARTBURN.* Unlike antacids which last only 1-3 hours
Show More
Top 2

Prilosec OTC Frequent Heartburn Medicine and Acid Reducer Tablets 42 Count - Omeprazole -

Prilosec
3700035907
0.03 Pounds
Seller CPR Rank Amazon Fulfilled Prime Free Shipping
TheBestShopDotCom -

Features

No.1 Doctor recommended OTC frequent heartburn treatment medicine for 10 straight years
No.1 Gastroenterologist recommended OTC frequent heartburn medicine for 10 straight years
Show More

Prilosec OTC, Omeprazole Delayed Release 20mg, Acid Reducer, Treats Frequent Heartburn for 24 Hour Relief, All Day, All Night*, Wildberry Flavor, 20mg, 42 Tablets

Prilosec
Value not found
4.813 x 2.375 x 3.688 inches
0.157 Pounds
Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Active Trade 6,606
HealthyHavenDeals -
Amazon.com -

Features

TREATS FREQUENT HEARTBURN: Heartburn medicine for those who experience heartburn flare ups 2+ times a week. Same Prilosec OTC, with a burst of Wildberry flavor
With 1 PRILOSEC OTC PILL EACH MORNING, 24 HOURS. ZERO HEARTBURN.* Unlike antacids which last only 1-3 hours
Show More

Prilosec OTC, Omeprazole Delayed Release 20mg, Acid Reducer, Treats Frequent Heartburn for 24 Hour Relief, All Day, All Night*, Heartburn Medicine, 20mg, Wildberry Flavor, 42 Tablets, (Pack of 2)

Prilosec
Value not found
4.813 x 2.375 x 3.688 Inches
0.314 pounds
Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -

Features

The information below is per-pack only
BLOCKS HEARTBURN BEFORE IT STARTS. Starts working on Day 1* to prevent excess acid production, tackling the root cause of your heartburn instead of just masking the symptoms
Show More

Prilosec OTC, Omeprazole Delayed Release 20mg, Acid Reducer, Treats Frequent Heartburn for 24 Hour Relief, All Day, All Night*, 20mg, 14 Tablets

Prilosec
3700035905
4.7 x 1.1 x 0.004 inches
0.02 pounds
Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Consensus LLC -
Amazon.com -

Features

TREATS FREQUENT HEARTBURN: Heartburn medicine for those who experience heartburn flare ups 2+ times a week
With 1 PRILOSEC OTC PILL in the morning, BLOCK HEARTBURN. ALL DAY. ALL NIGHT.*
Show More

Prilosec OTC Frequent Heartburn Medicine and Acid Reducer Tablets 28 Count (OLD)

Prilosec
1.7 x 4.9 x 3.7 inches
0.15 pounds
Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Active Trade 6,606
Premium Household 3,174

Features

See Brandstore for latest products
Top 7

Prilosec OTC Acid Reducer, Delayed-Release Tablets, 2 Pack-84 Count

Prilosec
2.3 x 4.8 x 3.7 Inches
0.25 Pounds
Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Silvery Health -

Features

Heartburn medicine for those who experience heartburn flare ups 2 or more times a week.
With one Prilosec OTC pill in the morning
Show More

Prilosec OTC Frequent Heartburn Relief Medicine and Acid Reducer 42 Tablets Omeprazole Delayed-Release Tablets 20mg - Proton Pump Inhibitor (OLD)

Prilosec
80348738
5.0 x 3.8 x 2.4 inches
0.15 pounds
Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -
Beauty Secret LA -
Bestdealsupplements -
Premium Household 3,174
ECOM EDGEZ INC -

Features

See Brandstore for latest products

Prilosec OTC, Omeprazole Delayed Release 20mg, Acid Reducer, Treats Frequent Heartburn for 24 Hour Relief, All Day, All Night*, Wildberry Flavor, 20mg, 14 Tablets

Prilosec
3
4.563 x 0.688 x 3.5 inches
0.0 pounds
Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Amazon.com -

Features

TREATS FREQUENT HEARTBURN: Heartburn medicine for those who experience heartburn flare ups 2+ times a week. Same Prilosec OTC, with a burst of Wildberry flavor
With 1 PRILOSEC OTC PILL EACH MORNING, 24 HOURS. ZERO HEARTBURN.* Unlike antacids which last only 1-3 hours
Show More

Prilosec 20.6 mg OTC, 42 Tablets (Pack of 3)

Prilosec
OTC
2.32 x 4.75 x 3.7 inches
0.09 Pounds
Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Reeks Work -
FBA556 -

Features

Brought to you by Prilosec
Buy in bulk & save!
Show More

Prilosec OTC (3 Pack) 42 tabs

Prilosec
125604
5.0 x 2.5 x 3.5 inches
0.11 pounds
Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Healthi Solutions -
Luxury Shop 4 Less -
FastPharma 8,792

Features

42 count, 3 pack of tablets
Works by directly blocking many of the active stomach pumps that produce acid before they start
Show More

Prilosec OTC Acid Reducer, Delayed-Release Tablets, Wildberry 42 ea (Pack of 2)

Prilosec
I00004015
6.0 x 4.0 x 4.0 inches
Seller CPR Rank Amazon Fulfilled Prime Free Shipping
ISKOLIVE 12 INC 2,115
TLC General Store -
TheBestShopDotCom -

Features

Item Package Length: 9.2cm
Item Package Width: 12.5cm
Show More

Prilosec OTC Acid Reducer, Delayed-Release Tablets, 42 Count

Prilosec
Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Goods Depot 6,261
TheBestShopDotCom -

Features

Reduces acid levels
Treats frequent heartburn
Show More
Top 14

Prilosec antacids OTC Delayed-release Acid Reducer, 3 Month Supply, 42 Count (Pack of 2)

Prilosec
6.0 x 5.0 x 4.0 inches
0.4894 Pounds
Seller CPR Rank Amazon Fulfilled Prime Free Shipping
YEAHGOSHOPPING, LLC -

Features

3 Pack of 14 tablets (42 Tablets) [Two Packs of 42, totally 84 tablets]
Not intended for immediate relief of heartburn
Show More

Prilosec OTC, Omeprazole Delayed Release, Acid Reducer, Treats Frequent Heartburn for 24 Hour Relief*, #1 Doctor Recommended Brand**, 28 Tablets

Prilosec
PR35906
1.7 x 4.9 x 3.7 inches
0.1 pounds
Seller CPR Rank Amazon Fulfilled Prime Free Shipping
Health4life LLC -
TheBestShopDotCom -
Amazon.com -

Features

TREATS FREQUENT HEARTBURN: Heartburn medicine for those who experience heartburn flare ups 2+ times a week. Same Prilosec OTC, with a burst of Wildberry flavor
With 1 PRILOSEC OTC PILL EACH MORNING, 24 HOURS. ZERO HEARTBURN.* Unlike antacids which last only 1-3 hours
Show More

Our Prilosec Review

Prilosec products on Amazon (Sep. 2026)

What to buy from Prilosec?

Prilosec sell products mainly in the Health & Household category.

Its popular products on Amazon include Antacids for Acid Reflux,Digestion & Nausea Medicine And Antacids for Heartburn

If you intend to buy any of these products, then you can find them easily on Amazon. 

Featured Reviews Related to Prilosec

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Prilosec Pricing

The brand has over 39 products listed on Amazon with a price range of $9.97 to $204.86 form our picks.

Currently, the average price of their product is $33.65 which is considered affordable. You can make your choice from the list of products offered by the Prilosec.

Is Prilosec a good brand? 

A brand is an essential factor when making a purchase. What do we think about the Prilosec? Well, according to the information available on Amazon, Prilosec products are sold by ISKOLIVE 12 INC.

The seller has received about 27,647 feedbacks from buyers with an average start rating of 4.8. With a rating as this from the number of feedbacks, we can conclude that Prilosec is Liquid error: comparison of String with 4.8 failed

Can I know who the owner of Prilosec is?

Prilosec is selling on Amazon's North America Marketplaces. You can find out the actual owner of the brand at https://www.uspto.gov/trademarks/search

From there, you can tell whether Amazon owns the brand or not. If you want to buy Amazon branded products, you can go here, and list some of their top brands. Amazon owns 100 private-label brands that operate in different markets.

Related Amazon Store for Prilosec

Similar Competitors Brands like Prilosec on Amazon


Methodology

How We Evaluated Prilosec Products

We are crawling & scraping a large amount of data from 39 Prilosec products and a countless number of reviews, you can gain valuable insights to enhance your understanding of various aspects related to Prilosec, and you can use those data to help you make informed buying Antacids for Acid Reflux,Digestion & Nausea Medicine And Antacids for Heartburn decisions. Those recommend the 15 best products from Prilosec based on thorough analysis and research by our CherryPicks-AI ranking system.

Why create this buying guide?

Our brand guide is designed to provide up-to-date & unbiased information about Prilosec products. Our goal is to empower you with data-driven insights, enabling you to make better shopping decisions efficiently to save time. We prioritize earning your trust by providing reliable information and guidance.


Top 10 Prilosec Sellers: CPR Seller Rank List

CPR sellers rank is based on CherryPicks-AI bestselling ranking system that helps us analyze each seller's sales trends. The List of top seller ranks is our in-house data, essential for our product ranking to help you make the right shopping choice.

Rank Name Yearly Feedbacks Avg. Ratings
🥇 ISKOLIVE 12 INC 27,647 4.8
🥈 Premium Household 19,545 4.8
🥉 MurMur Center 17,035 4.6
4 Goods Depot 10,726 4.9
5 Active Trade 10,160 4.9
6 Small shop BIG savings 7,949 4.9
7 FastPharma 7,747 4.9
8 Luxury Shop 4 Less 5,327 4.8
9 *Daily Deals* 5,004 4.7
10 Consensus LLC 4,820 4.9
ISKOLIVE 12 INC [27647] Premium Household [19545] MurMur Center [17035] Goods Depot [10726] Active Trade [10160] Small shop BIG savings [7949] FastPharma [7747] Luxury Shop 4 Less [5327] *Daily Deals* [5004] Consensus LLC [4820] ISKOLIVE 12 INC 24% Premium Household 17% MurMur Center 15% Goods Depot 9% Active Trade 9% Small shop BIG savings 7% FastPharma 7% Luxury Shop 4 Less 5% *Daily Deals* 4% Consensus LLC 4%